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1

Comparative effectiveness of axitinib versus sorafenib in advanced renal cell carcinoma (AXIS): a randomised phase 3 trial

Brian I Rini, Bernard Escudier, Piotr Tomczak, Andrey Kaprin, Cezary Szczylik, Thomas E Hutson, M Dror Michaelson, Vera A Gorbunova, Martin E Gore, Igor G Rusakov, Sylvie Negrier, Yen-Chuan Ou, Daniel

Journal:

Year:

2011

Language:

english

File:

PDF, 363 KB

english, 2011

2

A conserved NAD + binding pocket that regulates protein-protein interactions during aging

Li, Jun, Bonkowski, Michael S., Moniot, Sébastien, Zhang, Dapeng, Hubbard, Basil P., Ling, Alvin J. Y., Rajman, Luis A., Qin, Bo, Lou, Zhenkun, Gorbunova, Vera, Aravind, L., Steegborn, Clemens, Sincla

Journal:

Year:

2017

Language:

english

File:

PDF, 929 KB

english, 2017

3

How plants make ends meet: DNA double-strand break repair

Vera Gorbunova, Avraham A Levy

Journal:

Trends in Plant Science

Year:

1999

Language:

english

File:

PDF, 96 KB

english, 1999

4

Establishing Primary Adult Fibroblast Cultures From Rodents

Seluanov, Andrei, Vaidya, Amita, Gorbunova, Vera

Journal:

Journal of Visualized Experiments

Year:

2010

Language:

english

File:

PDF, 256 KB

english, 2010

5

High-molecular-mass hyaluronan mediates the cancer resistance of the naked mole rat

Tian, Xiao, Azpurua, Jorge, Hine, Christopher, Vaidya, Amita, Myakishev-Rempel, Max, Ablaeva, Julia, Mao, Zhiyong, Nevo, Eviatar, Gorbunova, Vera, Seluanov, Andrei

Journal:

Year:

2013

Language:

english

File:

PDF, 768 KB

english, 2013

6

Comparative genetics of longevity and cancer: insights from long-lived rodents

Gorbunova, Vera, Seluanov, Andrei, Zhang, Zhengdong, Gladyshev, Vadim N., Vijg, Jan

Journal:

Nature Reviews Genetics

Year:

2014

Language:

english

File:

PDF, 3.63 MB

english, 2014

7

DNA repair by nonhomologous end joining and homologous recombination during cell cycle in human cells

Mao, Zhiyong, Bozzella, Michael, Seluanov, Andrei, Gorbunova, Vera

Journal:

Year:

2008

Language:

english

File:

PDF, 399 KB

english, 2008

8

Dangerous Entrapment for NRF2

Gorbunova, Vera, Rezazadeh, Sarallah, Seluanov, Andrei

Journal:

Year:

2016

Language:

english

File:

PDF, 249 KB

english, 2016

9

Genetics of extreme human longevity to guide drug discovery for healthy ageing

Zhang, Zhengdong D., Milman, Sofiya, Lin, Jhih-Rong, Wierbowski, Shayne, Yu, Haiyuan, Barzilai, Nir, Gorbunova, Vera, Ladiges, Warren C., Niedernhofer, Laura J., Suh, Yousin, Robbins, Paul D., Vijg, J

Journal:

Nature Metabolism

Year:

2020

File:

PDF, 2.05 MB

2020

10

Short-term calorie restriction enhances DNA repair by non-homologous end joining in mice

Ke, Zhonghe, Firsanov, Denis, Spencer, Brianna, Seluanov, Andrei, Gorbunova, Vera

Journal:

npj Aging and Mechanisms of Disease

Year:

2020

File:

PDF, 730 KB

2020

11

A new hyperrecombinogenic mutant of Nicotiana tabacum

Vera Gorbunova, Naomi Avivi-Ragolski, Gil Shalev, Igor Kovalchuk, Shahal Abbo, Barbara Hohn, Avraham A. Levy

Journal:

The Plant Journal

Year:

2000

Language:

english

File:

PDF, 347 KB

english, 2000

12

Rodents for comparative aging studies: from mice to beavers

Vera Gorbunova, Michael J. Bozzella, Andrei Seluanov

Journal:

Year:

2008

Language:

english

File:

PDF, 177 KB

english, 2008

13

Telomerase activity coevolves with body mass not lifespan

Andrei Seluanov, Zhuoxun Chen, Christopher Hine, Tais H. C. Sasahara, Antonio A. C. M. Ribeiro, Kenneth C. Catania, Daven C. Presgraves, Vera Gorbunova

Journal:

Year:

2007

Language:

english

File:

PDF, 381 KB

english, 2007

14

Distinct tumor suppressor mechanisms evolve in rodent species that differ in size and lifespan

Andrei Seluanov, Christopher Hine, Michael Bozzella, Amelia Hall, Tais H. C. Sasahara, Antonio A. C. M. Ribeiro, Kenneth C. Catania, Daven C. Presgraves, Vera Gorbunova

Journal:

Year:

2008

Language:

english

File:

PDF, 863 KB

english, 2008

15

Analysis of DNA Double-strand Break (DSB) Repair in Mammalian Cells

Seluanov, Andrei, Mao, Zhiyong, Gorbunova, Vera

Journal:

Journal of Visualized Experiments

Year:

2010

Language:

english

File:

PDF, 381 KB

english, 2010

16

Changes in the level and distribution of Ku proteins during cellular senescence

Andrei Seluanov, Jacquelynn Danek, Nola Hause, Vera Gorbunova

Journal:

Year:

2007

Language:

english

File:

PDF, 1.14 MB

english, 2007

17

Genome-wide demethylation promotes triplet repeat instability independently of homologous recombination

Vincent Dion, Yunfu Lin, Brandee A. Price, Sharyl L. Fyffe, Andrei Seluanov, Vera Gorbunova, John H. Wilson

Journal:

Year:

2008

Language:

english

File:

PDF, 369 KB

english, 2008

18

Comparison of nonhomologous end joining and homologous recombination in human cells

Zhiyong Mao, Michael Bozzella, Andrei Seluanov, Vera Gorbunova

Journal:

Year:

2008

Language:

english

File:

PDF, 450 KB

english, 2008

19

Making ends meet in old age: DSB repair and aging

Vera Gorbunova, Andrei Seluanov

Journal:

Mechanisms of Ageing and Development

Year:

2005

Language:

english

File:

PDF, 211 KB

english, 2005

20

Coevolution of telomerase activity and body mass in mammals: From mice to beavers

Vera Gorbunova, Andrei Seluanov

Journal:

Mechanisms of Ageing and Development

Year:

2009

Language:

english

File:

PDF, 282 KB

english, 2009

21

SIRT1 as a therapeutic target in inflammaging of the pulmonary disease

Irfan Rahman, Vuokko L. Kinnula, Vera Gorbunova, Hongwei Yao

Journal:

Preventive Medicine

Year:

2012

Language:

english

File:

PDF, 340 KB

english, 2012

22

CLK-1 protein has DNA binding activity specific to OL region of mitochondrial DNA

Vera Gorbunova, Andrei Seluanov

Journal:

Year:

2002

Language:

english

File:

PDF, 335 KB

english, 2002

23

Bevacizumab plus interferon alfa-2a for treatment of metastatic renal cell carcinoma: a randomised, double-blind phase III trial

Bernard Escudier, Anna Pluzanska, Piotr Koralewski, Alain Ravaud, Sergio Bracarda, Cezary Szczylik, Christine Chevreau, Marek Filipek, Bohuslav Melichar, Emilio Bajetta, Vera Gorbunova, Jacques-Olivie

Journal:

Year:

2008

Language:

english

File:

PDF, 178 KB

english, 2008

24

Pharmacogenomics of cisplatin-based chemotherapy in ovarian cancer patients of different ethnic origins

Khrunin, Andrey, Ivanova, Feodosia, Moisseev, Alexey, Khokhrin, Denis, Sleptsova, Yuliya, Gorbunova, Vera, Limborska, Svetlana

Journal:

Pharmacogenomics

Year:

2012

Language:

english

File:

PDF, 612 KB

english, 2012

25

Rad51 Promoter-Targeted Gene Therapy Is Effective for In Vivo Visualization and Treatment of Cancer

Hine, Christopher M, Seluanov, Andrei, Gorbunova, Vera

Journal:

Molecular Therapy

Year:

2012

Language:

english

File:

PDF, 1022 KB

english, 2012

26

Low titre autoantibodies against recoverin in sera of patients with small cell lung cancer but without a loss of vision

Bazhin, Alexandr V., Shifrina, Olga N., Savchenko, Marina S., Tikhomirova, Natalya K., Goncharskaia, Maria A., Gorbunova, Vera A., Senin, Ivan I., Chuchalin, Alexandr G., Philippov, Pavel P.

Journal:

Year:

2001

Language:

english

File:

PDF, 135 KB

english, 2001

27

Capecitabine and cisplatin with or without cetuximab for patients with previously untreated advanced gastric cancer (EXPAND): a randomised, open-label phase 3 trial

Lordick, Florian, Kang, Yoon-Koo, Chung, Hyun-Cheol, Salman, Pamela, Oh, Sang Cheul, Bodoky, György, Kurteva, Galina, Volovat, Constantin, Moiseyenko, Vladimir M, Gorbunova, Vera, Park, Joon Oh, Sawak

Journal:

The Lancet Oncology

Year:

2013

Language:

english

File:

PDF, 323 KB

english, 2013

28

Enhanced cellular radiosensitivity induced by cofilin-1 over-expression is associated with reduced DNA repair capacity

Leu, Jyh-Der, Chiu, Yu-Wen, Lo, Chia-Chien, Chiang, Pei-Hsun, Chiu, Shu-Jun, Tsai, Cheng-Han, Hwang, Jeng-Jong, Chen, Ran-Chou, Gorbunova, Vera, Lee, Yi-Jang

Journal:

International Journal of Radiation Biology

Year:

2013

Language:

english

File:

PDF, 672 KB

english, 2013

29

Pharmacogenomic assessment of cisplatin-based chemotherapy outcomes in ovarian cancer

Khrunin, Andrey V, Khokhrin, Denis V, Moisseev, Alexey A, Gorbunova, Vera A, Limborska, Svetlana A

Journal:

Pharmacogenomics

Year:

2014

Language:

english

File:

PDF, 794 KB

english, 2014

30

DNA Repair by Homologous Recombination, But Not by Nonhomologous End Joining, Is Elevated in Breast Cancer Cells

Mao, Zhiyong, Jiang, Ying, Liu, Xiang, Seluanov, Andrei, Gorbunova, Vera

Journal:

Year:

2009

Language:

english

File:

PDF, 649 KB

english, 2009

31

SIRT6 represses LINE1 retrotransposons by ribosylating KAP1 but this repression fails with stress and age

Van Meter, Michael, Kashyap, Mehr, Rezazadeh, Sarallah, Geneva, Anthony J., Morello, Timothy D., Seluanov, Andrei, Gorbunova, Vera

Journal:

Nature Communications

Year:

2014

Language:

english

File:

PDF, 573 KB

english, 2014

32

Randomized Phase II Open-Label Study of mFOLFOX6 in Combination With Linifanib or Bevacizumab for Metastatic Colorectal Cancer

O'Neil, Bert H., Cainap, Calin, Van Cutsem, Eric, Gorbunova, Vera, Karapetis, Christos S., Berlin, Jordan, Goldberg, Richard M., Qin, Qin, Qian, Jiang, Ricker, Justin L., Fischer, JuDee, McKee, Mark D

Journal:

Clinical Colorectal Cancer

Year:

2014

Language:

english

File:

PDF, 911 KB

english, 2014

33

Brief report: A human induced pluripotent stem cell model of cernunnos deficiency reveals an important role for XLF in the survival of the primitive hematopoietic progenitors

Tilgner, Katarzyna, Neganova, Irina, Singhapol, Chatchawan, Saretzki, Gabriele, Al-Aama, Jumana Yousuf, Evans, Jerome, Gorbunova, Vera, Gennery, Andrew, Przyborski, Stefan, Stojkovic, Miodrag, Armstro

Journal:

Year:

2013

Language:

english

File:

PDF, 873 KB

english, 2013

34

SIRT6 overexpression induces massive apoptosis in cancer cells but not in normal cells

Van Meter, Michael, Mao, Zhiyong, Gorbunova, Vera, Seluanov, Andrei

Journal:

Year:

2011

Language:

english

File:

PDF, 2.92 MB

english, 2011

35

INK4 locus of the tumor-resistant rodent, the naked mole rat, expresses a functional p15/p16 hybrid isoform

Tian, Xiao, Azpurua, Jorge, Ke, Zhonghe, Augereau, Adeline, Zhang, Zhengdong D., Vijg, Jan, Gladyshev, Vadim N., Gorbunova, Vera, Seluanov, Andrei

Journal:

Proceedings of the National Academy of Sciences

Year:

2015

Language:

english

File:

PDF, 1.20 MB

english, 2015

36

SIRT6 rescues the age related decline in base excision repair in a PARP1-dependent manner

Xu, Zhu, Zhang, Lei, Zhang, Wenjun, Meng, Du, Zhang, Hongxia, Jiang, Ying, Xu, Xiaojun, Van Meter, Michael, Seluanov, Andrei, Gorbunova, Vera, Mao, Zhiyong

Journal:

Year:

2015

Language:

english

File:

PDF, 628 KB

english, 2015

37

A Correlative Biomarker Analysis of the Combination of Bevacizumab and Carboplatin-Based Chemotherapy for Advanced Nonsquamous Non–Small-Cell Lung Cancer

Mok, Tony, Gorbunova, Vera, Juhasz, Erzsebet, Szima, Barna, Burdaeva, Olga, Orlov, Sergey, Yu, Chong-Jen, Archer, Venice, Hilton, Magalie, Delmar, Paul, Pallaud, Celine, Reck, Martin

Journal:

Journal of Thoracic Oncology

Year:

2014

Language:

english

File:

PDF, 495 KB

english, 2014

38

Forever young? Exploring the link between rapamycin, longevity and cancer

Van Meter, Michael, Seluanov, Andrei, Gorbunova, Vera

Journal:

Year:

2012

Language:

english

File:

PDF, 162 KB

english, 2012

39

Regulation of Rad51 promoter

Hine, Christopher M, Li, Hongjie, Xie, Li, Mao, Zhiyong, Seluanov, Andrei, Gorbunova, Vera

Journal:

Year:

2014

Language:

english

File:

PDF, 956 KB

english, 2014

40

Axitinib for the Treatment of Metastatic Renal Cell Carcinoma

Larkin, James, Fishman, Mayer, Wood, Laura, Negrier, Sylvie, Olivier, Kara, Pyle, Linda, Gorbunova, Vera, Jonasch, Eric, Andrews, Lori, Staehler, Michael

Journal:

American Journal of Clinical Oncology

Year:

2014

Language:

english

File:

PDF, 150 KB

english, 2014

41

Knock-In Reporter Mice Demonstrate that DNA Repair by Non-homologous End Joining Declines with Age

Vaidya, Amita, Mao, Zhiyong, Tian, Xiao, Spencer, Brianna, Seluanov, Andrei, Gorbunova, Vera, Hasty, Paul

Journal:

Year:

2014

Language:

english

File:

PDF, 1.32 MB

english, 2014

42

Doxorubicin and Paclitaxel versus Fluorouracil, Doxorubicin and Cyclophosphamide as First-Line Therapy for Women with Advanced Breast Cancer: Long-Term Analysis of the Previously Published Trial

Jassem, Jacek, Pienkowski, Tadeusz, Pluzanska, Anna, Jelic, Svetislav, Gorbunova, Vera, Berzins, Juris, Nagykalnai, Thomas, Biganzoli, Laura, Aloe, Alessandra, Astier, Ludovic, Munier, Stephane

Journal:

Year:

2009

Language:

english

File:

PDF, 181 KB

english, 2009

43

Health-Related Quality of Life in Patients with Advanced Nonsquamous Non–Small-Cell Lung Cancer Receiving Bevacizumab or Bevacizumab-Plus-Pemetrexed Maintenance Therapy in AVAPERL (MO22089)

Rittmeyer, Achim, Gorbunova, Vera, Vikström, Anders, Scherpereel, Arnaud, Kim, Joo-Hang, Ahn, Myung-Ju, Chella, Antonio, Chouaid, Christos, Campbell, Alicyn K., Barlesi, Fabrice

Journal:

Journal of Thoracic Oncology

Year:

2013

Language:

english

File:

PDF, 269 KB

english, 2013

44

Organization of the Mammalian Ionome According to Organ Origin, Lineage Specialization, and Longevity

Ma, Siming, Lee, Sang-Goo, Kim, Eun Bae, Park, Thomas J., Seluanov, Andrei, Gorbunova, Vera, Buffenstein, Rochelle, Seravalli, Javier, Gladyshev, Vadim N.

Journal:

Year:

2015

Language:

english

File:

PDF, 2.76 MB

english, 2015

45

DNA double strand break repair, aging and the chromatin connection

Gorbunova, Vera, Seluanov, Andrei

Journal:

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

Year:

2016

Language:

english

File:

PDF, 969 KB

english, 2016

46

Telomerase as a Growth-Promoting Factor

Gorbunova, Vera, Seluanov, Andrei

Journal:

Year:

2003

Language:

english

File:

PDF, 74 KB

english, 2003

47

Comparative analysis of genome maintenance genes in naked mole rat, mouse, and human

MacRae, Sheila L., Zhang, Quanwei, Lemetre, Christophe, Seim, Inge, Calder, Robert B., Hoeijmakers, Jan, Suh, Yousin, Gladyshev, Vadim N., Seluanov, Andrei, Gorbunova, Vera, Vijg, Jan, Zhang, Zhengdon

Journal:

Year:

2015

Language:

english

File:

PDF, 201 KB

english, 2015

48

Safety and Efficacy of First-Line Bevacizumab Plus Chemotherapy in Elderly Patients with Advanced or Recurrent Nonsquamous Non-small Cell Lung Cancer: Safety of Avastin in Lung trial (MO19390)

Laskin, Janessa, Crinò, Lucio, Felip, Enriqueta, Franke, Fabio, Gorbunova, Vera, Groen, Harry, Jiang, Guo-liang, Reck, Martin, Schneider, Claus-Peter

Journal:

Journal of Thoracic Oncology

Year:

2012

Language:

english

File:

PDF, 213 KB

english, 2012

49

Pericellular Brush and Mechanics of Guinea Pig Fibroblast Cells Studied with AFM

Dokukin, Maxim, Ablaeva, Yulija, Kalaparthi, Vivekanand, Seluanov, Andrei, Gorbunova, Vera, Sokolov, Igor

Journal:

Biophysical Journal

Year:

2016

Language:

english

File:

PDF, 1.82 MB

english, 2016

50

JNK Phosphorylates SIRT6 to Stimulate DNA Double-Strand Break Repair in Response to Oxidative Stress by Recruiting PARP1 to DNA Breaks

Van Meter, Michael, Simon, Matthew, Tombline, Gregory, May, Alfred, Morello, Timothy D., Hubbard, Basil P., Bredbenner, Katie, Park, Rosa, Sinclair, David A., Bohr, Vilhelm A., Gorbunova, Vera, Seluan

Journal:

Year:

2016

Language:

english

File:

PDF, 2.35 MB

english, 2016